CREGS00003 (DAF-3 Version 1)

From CREGS

Sequence Logo (What is a sequence logo ?)

IUPAC Consensus Sequence (What is the IUPAC code ?)

GTCTG[1]

Regulatory element length

5 base pairs

Status

Tested both in vivo & in vitro

Predicted by Experiment

Description & Comments

Expressed throughout development. Daf-5 might also bind same bs.

Similarity to other CREGS motifs

CREGS00052 (0.800 Rev. Comp. ) CREGS00076 (0.800) CREGS00056_(DAF-12 Version 1) (0.860 Rev. Comp. ) CREGS00024 (0.800 Rev. Comp. ) CREGS00021 (0.800) CREGS00040_(MIR-273 Version 2) (0.800) CREGS00064 (0.867) CREGS00065 (0.810) CREGS00066 (0.806 Rev. Comp. ) CREGS00067 (0.803 Rev. Comp. ) [[| (0.000)]]

Similarity to motifs in other organisms

Motif bound by

DAF-3 [1]

Expression Pattern

• Expressed
• Tissues & cells:
  • pharynx
  • nervous system
  • gut

References

1. Thatcher JD, Haun C, and Okkema PG. The DAF-3 Smad binds DNA and represses gene expression in the Caenorhabditis elegans pharynx. Development 1999 Jan; 126(1) 97-107. pmid:9834189. PubMed HubMed [KEY-9834189]

All Medline abstracts: PubMed HubMed

Motif Representation Formats

Information Content Matrix (Total IC 10 )

A [  0.00 0.00 0.00 0.00 0.00 ]
C [  0.00 0.00 2.00 0.00 0.00 ]
G [  2.00 0.00 0.00 0.00 2.00 ]
T [  0.00 2.00 0.00 2.00 0.00 ]

Position Frequency Matrix

A [    0   0   0   0   0 ]
C [    0   0  12   0   0 ]
G [   12   0   0   0  12 ]
T [    0  12   0  12   0 ]

Position Weight Matrix

A [  -2.16 -2.16 -2.16 -2.16 -2.16 ]
C [  -2.16 -2.16  1.73 -2.16 -2.16 ]
G [   1.73 -2.16 -2.16 -2.16  1.73 ]
T [  -2.16  1.73 -2.16  1.73 -2.16 ]